Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJM2H1)

Drug Name

4-(benzylideneamino)benzoic acid Drug Info

Synonyms

4-(benzylideneamino)benzoic Acid; CHEMBL567820; 820985-82-8; AC1LEKUN; SCHEMBL11027747; SCHEMBL10354517; ZINC56233; CTK3E2373; DTXSID10350765; MolPort-000-420-278; 4-(a-benzylideneamino)benzoic acid; benzylideneaniline-p-carboxylic acid; STK861975; BDBM50299292; AKOS002162184; MCULE-4796916281; 4-((1E)-2-phenyl-1-azavinyl)benzoic acid; ST45187403; 4-{[(E)-phenylmethylidene]amino}benzoic acid; Benzoic acid, 4-[(E)-(phenylmethylene)amino]-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 687887
CAS Number: CAS 820985-82-8
TTD Drug ID: DMJM2H1

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Carbonic anhydrase II (CA-II)	DTT	CA2	8.796	10.933	9.395	9.819

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase II (CA-II)	DTT	CA2	7.95E-08	0.52	0.33

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Carbonic anhydrase II-induced selection of inhibitors from a dynamic combinatorial library of Schiff's bases. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6014-7.