Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJPBAX)

Drug Name

Oxybutynine Drug Info

Synonyms

5633-20-5; Ditropan; Oxytrol; Oxibutyninum; Oxybutyninum; Oxibutinina; Oxybutyninum [INN-Latin]; Oxybutynine [INN-French]; Oxybutinin; Cystrin; Oxibutinina [INN-Spanish]; Oxybutynin Base; transdermal patch; Lyrinel XL; Oxybutynin [USAN:INN:BAN]; 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat; CCRIS 1923; oxybutynin topical gel; Ditropan Xl; Oxybutynin (Ditropan); HSDB 3270; 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate; CHEMBL1231; Cyclohexaneglycolic acid, alpha-phenyl-, 4-(diethylamino)-2-b

Indication

Disease Entry	ICD 11	Status	REF
Obsolete neurogenic bladder		Approved	[1]
Discovery agent	N.A.	Investigative	[2]
Priapism		Investigative	[1]

Cross-matching ID

PubChem CID: 4634
ChEBI ID: CHEBI:7856
CAS Number: CAS 5633-20-5
TTD Drug ID: DMJPBAX
ACDINA Drug ID: D00501

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Muscarinic acetylcholine receptor M3 (CHRM3)	TTQ13Z5	ACM3_HUMAN	Antagonist	[2]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Obsolete neurogenic bladder

ICD Disease Classification

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Muscarinic acetylcholine receptor M3 (CHRM3)	DTT	CHRM3	4.61E-07	-0.59	-0.73

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	A standard database for drug repositioning. Sci Data. 2017 Mar 14;4:170029.
2	Generation of an agonistic binding site for blockers of the M(3) muscarinic acetylcholine receptor. Biochem J. 2008 May 15;412(1):103-12.