Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMJXE6K)

Drug Name

GNF-PF-607 Drug Info

Synonyms

GNF-PF-607; CHEMBL113999; 13794-67-7; N6-[(3,4,5-trimethoxyphenyl)methyl]quinazoline-2,4,6-triamine; NSC156246; AC1L6FHM; AC1Q4YN2; n6-(3,4,5-trimethoxybenzyl)quinazoline-2,4,6-triamine; CTK0I1910; DTXSID70303050; BDBM50066492; NSC-156246; 6-[(3,4,5-Trimethoxybenzyl)amino]quinazoline-2,4-diamine; N*6*-(3,4,5-Trimethoxy-benzyl)-quinazoline-2,4,6-triamine; 6-N-[(3,4,5-trimethoxyphenyl)methyl]quinazoline-2,4,6-triamine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 291270
CAS Number: CAS 13794-67-7
TTD Drug ID: DMJXE6K

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Polypeptide deformylase (PDF)	TT9SL3Q	DEFM_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Polypeptide deformylase (PDF)	DTT	PDF	8.87E-16	-0.54	-0.86

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	CoMFA and CoMSIA analyses of Pneumocystis carinii dihydrofolate reductase, Toxoplasma gondii dihydrofolate reductase, and rat liver dihydrofolate r... J Med Chem. 2005 Mar 10;48(5):1448-69.