Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMK1LZD)

Drug Name

Methoxy polyethylene glycol-epoetin beta Drug Info

Synonyms

Mircera (TN)

Indication

Disease Entry	ICD 11	Status	REF
Kidney transplant rejection	NE84	Approved	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Erythropoietin Receptor (EPOR)	TTAUX24	EPOR_HUMAN	Activator	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Erythropoietin Receptor (EPOR)	DTT	EPOR	5.166	4.594	4.469	4.763

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Kidney transplant rejection

ICD Disease Classification

NE84

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Erythropoietin Receptor (EPOR)	DTT	EPOR	7.04E-01	0.11	0.27

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	2007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9.