Details of the Drug

General Information of Drug (ID: DMK1LZD)

Drug Name

Methoxy polyethylene glycol-epoetin beta

Synonyms

Mircera (TN)

Indication

Disease Entry	ICD 11	Status	REF
Kidney transplant rejection	NE84	Approved	[1]
------------------------------------------------------------------------------------

ADMET Property

Half-life: The concentration or amount of drug in body reduced by one-half in 134 +/- 65 hours [2]
Metabolism: The drug is not metabolised []
Vd: The volume of distribution (Vd) of drug is 0.095 L/kg []

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Erythropoietin Receptor (EPOR)	TTAUX24	EPOR_HUMAN	Activator	[1]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Kidney transplant rejection

ICD Disease Classification

NE84

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Erythropoietin Receptor (EPOR)	DTT	EPOR	7.04E-01	0.11	0.27

Molecular Expression Atlas (MEA)

Jump to Detail Molecular Expression Atlas of This Drug

References

1	2007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9.
2	Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds