Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMKMJHE)

• Drug Name: Cemiplimab Drug Info
• Synonyms: REGN2810; REGN-2810; REGN 2810

Indication

Disease Entry	ICD 11	Status	REF
Cutaneous squamous cell carcinoma	2C30	Approved	[1]

• Cross-matching ID: TTD Drug ID: DMKMJHE

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Programmed cell death protein 1 (PD-1)	TTNBFWK	PDCD1_HUMAN	Modulator	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Programmed cell death protein 1 (PD-1)	DTT	PDCD1	5.635	4.661	4.706	5.15

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Cutaneous squamous cell carcinoma
• ICD Disease Classification: 2C30

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Programmed cell death protein 1 (PD-1)	DTT	PDCD1	7.26E-01	-0.01	-0.03

References

• [1] 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.