General Information of Drug (ID: DMKRHQ3)

Drug Name
4-methyl-2H-benzofuro[3,2-g]chromen-2-one Drug Info
Synonyms
CHEMBL201777; 105290-13-9; 2H-Benzofuro(3,2-g)-1-benzopyran-2-one, 4-methyl-; 4-Methyl-(1)benzofuro(3,2-g)chromen-2-one; 2H-Benzofuro[3,2-g]-1-benzopyran-2-one, 4-methyl-; 4-methyl-[1]benzofuro[3,2-g]chromen-2-one; 4-methyl-2H-benzofuro[3,2-g]chromen-2-one; ACMC-20c6p3; AC1Q6A2V; AC1L4EY2; 4-methyl-2h-[1]benzofuro[3,2-g]chromen-2-one; CTK0G5617; DTXSID00147060; ZINC6069630; BDBM50181850
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
184462
CAS Number
CAS 105290-13-9
TTD Drug ID
DMKRHQ3

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type A (MAO-A) TT3WG5C AOFA_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Monoamine oxidase type A (MAO-A) DTT MAOA 7.207 8.159 9.043 7.711
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Monoamine oxidase type A (MAO-A) DTT MAOA 8.14E-01 0.05 0.1
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 A QSAR model for in silico screening of MAO-A inhibitors. Prediction, synthesis, and biological assay of novel coumarins. J Med Chem. 2006 Feb 9;49(3):1149-56.