General Information of Drug (ID: DMLT01H)

Drug Name
6-Bromo-2-piperazin-1-yl-quinoline Drug Info
Synonyms
124782-95-2; 6-Bromo-2-piperazin-1-yl-quinoline; 6-bromo-2-(piperazin-1-yl)quinoline; 6-Bromoquipazine; 6-bromo-2-piperazin-1-ylquinoline; Quinoline, 6-bromo-2-(1-piperazinyl)-; CHEMBL39164; Quinoline,6-bromo-2-(1-piperazinyl)-; ACMC-20mr6z; AC1L2X2K; SCHEMBL5912936; CTK4B4077; DTXSID90154485; MKIHFWMBAKJYJL-UHFFFAOYSA-N; ZINC2527449; BDBM50090213; 6-bromo-2-(1-piperazinyl)quinoline; 3453AJ; AKOS022401899; AB19846; 6-bromanyl-2-piperazin-1-yl-quinoline; AJ-83658; DB-062320; AX8027344; FT-0713002; Z-6757; A805296
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
130261
CAS Number
CAS 124782-95-2
TTD Drug ID
DMLT01H

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serotonin transporter (SERT) TT3ROYC SC6A4_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Serotonin transporter (SERT) DTT SLC6A4 6.278 5.469 6.075 6.966
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Serotonin transporter (SERT) DTT SLC6A4 8.76E-01 7.18E-05 6.19E-04
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 1. Bioorg Med Chem Lett. 2000 Jul 17;10(14):1559-62.