General Information of Drug (ID: DMM1IAU)

Drug Name
PHENYLTHIOUREA Drug Info
Synonyms
Phenylthiourea; N-Phenylthiourea; 1-Phenylthiourea; 103-85-5; 1-PHENYL-2-THIOUREA; Phenylthiocarbamide; Thiourea, phenyl-; Phenyl-2-thiourea; Urea, 1-phenyl-2-thio-; phenyl-thiourea; Thiourea, N-phenyl-; Fenylthiomocovina; USAF EK-1569; RCRA waste number P093; NCI-C02017; CCRIS 514; Fenylthiomocovina [Czech]; NSC 5779; N-Phenyl-Thiourea; N-phenylisothiourea; alpha-Phenylthiourea; U 6324; UNII-6F82C6Q54C; HSDB 4105; .alpha.-Phenylthiourea; EINECS 203-151-2; RCRA waste no. P093; AI3-07549; CHEMBL263376; CHEBI:46261
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
676454
ChEBI ID
CHEBI:46261
CAS Number
CAS 103-85-5
TTD Drug ID
DMM1IAU

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tyrosinase (TYR) TTULVH8 TYRO_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Tyrosinase (TYR) DTT TYR 5.959 5.711 5.973 4.912
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tyrosinase (TYR) DTT TYR 6.68E-04 2.54 1.15
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Analogues of N-hydroxy-N'-phenylthiourea and N-hydroxy-N'-phenylurea as inhibitors of tyrosinase and melanin formation. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3607-10.