Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMMYENH)

Drug Name

5-cyclohexyl-1,3,4-oxadiazole-2(3H)-thione Drug Info

Synonyms

5-cyclohexyl-1,3,4-oxadiazole-2-thiol; 173589-87-2; 5-Cyclohexyl-[1,3,4]oxadiazole-2-thiol; CHEMBL456586; 5-cyclohexyl-1,3,4-oxadiazole-2(3H)-thione; 1,3,4-Oxadiazole-2(3H)-thione, 5-cyclohexyl-; BAS 09627004; AC1Q7GLG; AC1MWQ13; MLS000719170; SCHEMBL13401036; CTK0A7651; DTXSID20396654; MolPort-000-932-255; HMS1700P22; HMS2732D23; ZINC6675630; BDBM50320725; AKOS000669727; MCULE-5633296933; SMR000291438; KB-124591; 5-cyclohexyl-3H-1,3,4-oxadiazole-2-thione; EN300-10672; 5-Cyclohexyl-3H-[1,3,4]oxadiazole-2-thione; K-5320

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 3803233
CAS Number: CAS 173589-87-2
TTD Drug ID: DMMYENH

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosinase (TYR)	TTULVH8	TYRO_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Tyrosinase (TYR)	DTT	TYR	5.959	5.711	5.973	4.912

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tyrosinase (TYR)	DTT	TYR	6.68E-04	2.54	1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triaz... Bioorg Med Chem. 2010 Jun 1;18(11):4042-8.