Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMMZ79C)

Drug Name
CER-227185 Drug Info
Synonyms TCTP inhibitor (cancer), Cerenis; Translationally controlled tumor protein inhibitor (acute myeloid leukemia), Cerenis
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Discontinued in Phase 1/2 [1]
Cross-matching ID
TTD Drug ID
DMMZ79C

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Translationally-controlled tumor protein (TPT1) TT3PTB6 TCTP_HUMAN Inhibitor [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Translationally-controlled tumor protein (TPT1) DTT TPT1 12.492 12.257 12.301 12.265
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Acute myeloid leukaemia
ICD Disease Classification 2A60
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Translationally-controlled tumor protein (TPT1) DTT TPT1 1.08E-17 0.1 1.22
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026293)
2 Clinical pipeline report, company report or official report of Cerep.