Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMN0XJQ)

Drug Name
Isoflavone derivative 8 Drug Info
Synonyms PMID26666870-Compound-26
Cross-matching ID
TTD Drug ID
DMN0XJQ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Smoothened homolog (SMO) TT8J1S3 SMO_HUMAN Inhibitor [1]
Zinc finger protein GLI1 (Gli1) TTJOMH6 GLI1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Smoothened homolog (SMO) DTT SMO 4.01E-06 -0.18 -0.35
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Evaluation of WO2014207069 A1: Multitarget Hedgehog pathway inhibitors and uses thereof.Expert Opin Ther Pat. 2016;26(4):529-35.