Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMN6IDO)

• Drug Name: GTP-010 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Dyspepsia	MD92	Phase 2	[1]
Irritable bowel syndrome	DD91.0	Phase 2	[1]

• Cross-matching ID: TTD Drug ID: DMN6IDO

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glucagon-like peptide 1 receptor (GLP1R)	TTVIMDE	GLP1R_HUMAN	Agonist	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Glucagon-like peptide 1 receptor (GLP1R)	DTT	GLP1R	2	2.848	3.472	2.963

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• ICD Disease Classification: 13 Disease of the digestive system
• Disease Class: ICD-11: DD91 Irritable bowel syndrome
• The Studied Tissue: Rectal colon tissue
• The Studied Disease: Irritable bowel syndrome [ICD-11:DD91.0]

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Glucagon-like peptide 1 receptor (GLP1R)	DTT	GLP1R	5.36E-01	-0.01	-0.06

References

• [1] Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.