Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMNARJT)

Drug Name
Ioflupane i-123 Drug Info
Synonyms Datscan (TN)
Indication
Disease Entry ICD 11 Status REF
Parkinson disease 8A00.0 Approved [1]
Cross-matching ID
PubChem CID
3086674
ChEBI ID
CHEBI:68855
CAS Number
CAS 155798-07-5
TTD Drug ID
DMNARJT
VARIDT Drug ID
DR01147
ACDINA Drug ID
D01171

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine transporter (DAT) TTVBI8W SC6A3_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Dopamine transporter (DAT) DTT SLC6A3 4 2.609 5.233 3.7
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Parkinson disease
ICD Disease Classification 8A00.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Dopamine transporter (DAT) DTT SLC6A3 1.08E-03 -3.08 -1.99
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 2011 FDA drug approvals. Nat Rev Drug Discov. 2012 Feb 1;11(2):91-4.
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015