Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMNETSX)

Drug Name
Acerogenin C Drug Info
Synonyms acerogenin C; SCHEMBL4112475
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
10040223
TTD Drug ID
DMNETSX
VARIDT Drug ID
DR00884

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SLC5A2 messenger RNA (SLC5A2 mRNA) TTF8JAT SC5A2_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
SLC5A2 messenger RNA (SLC5A2 mRNA) DTT SLC5A2 5.466 5.271 7.359 3.573
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
SLC5A2 messenger RNA (SLC5A2 mRNA) DTT SLC5A2 3.26E-01 -0.09 -0.37
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Cyclic diarylheptanoids as Na+-glucose cotransporter (SGLT) inhibitors from Acer nikoense. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1070-4.