Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMNIYSZ)

Drug Name
RP101 Drug Info
Synonyms SCHEMBL15589316; CHEMBL3703295; BDBM149820; US8975415,
Indication
Disease Entry ICD 11 Status REF
Infectious disease 1A00-CA43.1 Phase 2/3 [1]
Pancreatic cancer 2C10 Phase 2/3 [1]
Cross-matching ID
PubChem CID
446727
CAS Number
CAS 69304-47-8
TTD Drug ID
DMNIYSZ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Thymidine kinase 1 (TK1) TTP3QRF KITH_HUMAN Inhibitor [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Thymidine kinase 1 (TK1) DTT TK1 5.524 5.296 5.963 6.272
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Infectious disease
ICD Disease Classification 1A00-CA43.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Thymidine kinase 1 (TK1) DTT TK1 1.14E-03 0.26 0.75
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020300)
2 DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.