Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMNTURD)

Drug Name
Ranagengliotucel-T Drug Info
Synonyms Glionix; Brain tumor vaccine, NovaRx; Antisense (TGFbeta) brain tumor vaccine, NovaRx
Indication
Disease Entry ICD 11 Status REF
Brain cancer 2A00 Discontinued in Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMNTURD

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
TGF beta-2 messenger RNA (TGFB2 mRNA) TTI0KH6 TGFB2_HUMAN Not Available [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
TGF beta-2 messenger RNA (TGFB2 mRNA) DTT TGFB2 5.307 4.868 4.76 5.406
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Brain cancer
ICD Disease Classification 2A00
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
TGF beta-2 messenger RNA (TGFB2 mRNA) DTT TGFB2 1.51E-17 -0.53 -0.77
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017210)
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017210)