Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMNUM4K)

Drug Name

3-hydroxybenzylhydrazine Drug Info

Synonyms

3-hydroxybenzylhydrazine; 3-(hydrazinylmethyl)phenol; 637-33-2; 3-(Hydrazinomethyl)phenol; Nsd 1015; m-Hydroxybenzyl hydrazine; UNII-A27K5Q85R2; 3-Hydrazinomethyl-phenol; BRN 1841459; HYDRAZINE, 1-(3-HYDROXYBENZYL)-; CHEMBL352205; NSD-1015; A27K5Q85R2; 3-hydroxy-benzylhydrazine; C7H10N2O; m-hydroxybenzylhydrazine; Phenol,3-(hydrazinylmethyl)-; Spectrum_000313; SpecPlus_000785; AC1L1BYI; Spectrum4_001209; Spectrum5_001883; Spectrum3_000726; Lopac-H-9382; Lopac0_000597; BSPBio_002252; KBioGR_001618; 3-(Hydrazinomethyl)phenol #

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 1663
ChEBI ID: CHEBI:104133
CAS Number: CAS 637-33-2
TTD Drug ID: DMNUM4K

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Aromatic-L-amino-acid decarboxylase (DDC)	TTN451K	DDC_HUMAN	Inhibitor	[2]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Aromatic-L-amino-acid decarboxylase (DDC)	DTT	DDC	7.255	7.312	8.596	9.191

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Aromatic-L-amino-acid decarboxylase (DDC)	DTT	DDC	7.84E-03	-1.49	-1.01

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5116).
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1271).