General Information of Drug (ID: DMNWP02)

Drug Name
S-hexylglutathione Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
97536
ChEBI ID
CHEBI:27704
CAS Number
CAS 24425-56-7
TTD Drug ID
DMNWP02

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glutathione-dependent PGD synthase (HPGDS) TTCYE56 HPGDS_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Glutathione-dependent PGD synthase (HPGDS) DTT HPGDS 6.186 5.744 5.641 7.445
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glutathione-dependent PGD synthase (HPGDS) DTT HPGDS 1.63E-05 0.34 0.71
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Purification and catalytic properties of glutathione transferase from the hepatopancreas of crayfish macrobrachium vollenhovenii (herklots). J Biochem Mol Toxicol. 2004;18(6):332-44.