General Information of Drug (ID: DMO10FD)

Drug Name
1-(Propan-2-ylidene)thiosemicarbazide Drug Info
Synonyms
Acetone thiosemicarbazone; 1752-30-3; Thiosemicarbazone acetone; ACETONE THIOSEMICARBAZIDE; Acetone, thiosemicarbazone; Hydrazinecarbothioamide, 2-(1-methylethylidene)-; Acetonthiosemikarbazon; Acetonethiosemicarbazone; 2-(1-Methylethylidene)hydrazinecarbothioamide; NSC 711; Acetonthiosemikarbazon [Czech]; UNII-C3U604L47F; HSDB 6422; EINECS 217-137-9; (isopropylideneamino)thiourea; AI3-22961; CHEMBL500557; (propan-2-ylideneamino)thiourea; C3U604L47F; 2-(propan-2-ylidene)hydrazinecarbothioamide; WLN: SUYZMNUY1& AC1MCI32
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
2770166
CAS Number
CAS 1752-30-3
TTD Drug ID
DMO10FD

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tyrosinase (TYR) TTULVH8 TYRO_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Tyrosinase (TYR) DTT TYR 5.959 5.711 5.973 4.912
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tyrosinase (TYR) DTT TYR 6.68E-04 2.54 1.15
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 A class of potent tyrosinase inhibitors: alkylidenethiosemicarbazide compounds. Eur J Med Chem. 2009 Apr;44(4):1773-8.