Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMO2S6T)

Drug Name
MOXIFETIN HYDROGEN MALEATE Drug Info
Synonyms VUFB-15468; 2-(3-Hydroxyphenylsulfanyl)-N,N-dimethylbenzylamine hydrogen maleate; 3-[2-(Dimethylaminomethyl)phenylsulfanyl]phenol hydrogen maleate
Indication
Disease Entry ICD 11 Status REF
Mood disorder 6A60-6E23 Terminated [1]
Cross-matching ID
PubChem CID
6918142
TTD Drug ID
DMO2S6T

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serotonin transporter (SERT) TT3ROYC SC6A4_HUMAN Not Available [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Serotonin transporter (SERT) DTT SLC6A4 6.278 5.469 6.075 6.966
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Mood disorder
ICD Disease Classification 6A60-6E23
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Serotonin transporter (SERT) DTT SLC6A4 8.76E-01 7.18E-05 6.19E-04
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001731)
2 Moxidectin causes adult worm mortality of human lymphatic filarial parasite Brugia malayi in rodent models. Folia Parasitol (Praha). 2014 Dec;61(6):561-70.