General Information of Drug (ID: DMP9EJ7)

Drug Name
CM-2236 Drug Info
Synonyms Psychomodulator (post-traumatic stress disorder), Cenomed BioSciences
Indication
Disease Entry ICD 11 Status REF
Post-traumatic stress disorder 6B40 Preclinical [1]
Cross-matching ID
TTD Drug ID
DMP9EJ7

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 1A receptor (HTR1A) TTSQIFT 5HT1A_HUMAN Agonist [2]
Adrenergic receptor alpha-1A (ADRA1A) TTNGILX ADA1A_HUMAN Agonist [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
5-HT 1A receptor (HTR1A) DTT HTR1A 4.661 5.289 3.053 3.472
Adrenergic receptor alpha-1A (ADRA1A) DTT ADRA1A 3.154 3.853 4.129 2.963
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Post-traumatic stress disorder
ICD Disease Classification 6B40
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
5-HT 1A receptor (HTR1A) DTT HTR1A 2.18E-01 -0.11 -0.51
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029346)
2 CN patent application no. 104151292, Indole derivative or a pharmaceutically acceptable salt thereof.