Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMPL395)

Drug Name
Insulin degludec Drug Info
Synonyms Tresiba (TN)
Indication
Disease Entry ICD 11 Status REF
Type-1/2 diabetes 5A10-5A11 Approved [1]
Cross-matching ID
PubChem CID
118984462
CAS Number
CAS 844439-96-9
TTD Drug ID
DMPL395
ACDINA Drug ID
D01163

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Insulin (INS) TTZOPHG INS_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Insulin (INS) DTT INS 0.848 2.138 0.379 0.926
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Type-1/2 diabetes
ICD Disease Classification 5A10-5A11
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Insulin (INS) DTT INS 6.70E-01 -0.12 -0.46
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Radium 223 dichloride for prostate cancer treatment. Drug Des Devel Ther. 2017 Sep 6;11:2643-2651.