Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMPNGXE)

Drug Name

2-(2-cyclohexylidenehydrazinyl)-4-phenylthiazole Drug Info

Synonyms

CHEMBL220495; 2-(2-cyclohexylidenehydrazinyl)-4-phenylthiazole; AC1P6Q43; SCHEMBL19017688; ZINC7350105; BDBM50326652; AKOS005139675; ST51067929; N-(cyclohexylideneamino)-4-phenyl-thiazol-2-amine; 1-cyclohexylidene-2-(4-phenylthiazol-2-yl)hydrazine; N-(cyclohexylideneamino)-4-phenyl-1,3-thiazol-2-amine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 8443728
TTD Drug ID: DMPNGXE

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Monoamine oxidase type B (MAO-B)	TTGP7BY	AOFB_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Monoamine oxidase type B (MAO-B)	DTT	MAOB	9.367	6.907	8.237	8.409

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Monoamine oxidase type B (MAO-B)	DTT	MAOB	2.65E-02	1.12E-02	0.07

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors. Bioorg Med Chem. 2010 Jul 15;18(14):5063-70.