Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMPSOIF)

Drug Name

6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE Drug Info

Synonyms

6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE; 6-Hydroxy-2-benzothiazolesulfonamide; CHEMBL6685; 6-Hydroxybenzothiazole-2-sulfonamide; ZEC; 1zfq; AC1OA9RN; SCHEMBL160105; BDBM10874; NOOBQTYVTDBXTL-UHFFFAOYSA-N; AKOS022657291; aromatic/heteroaromatic sulfonamide 19; DB08765

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 6852129
CAS Number: CAS 29927-14-8
TTD Drug ID: DMPSOIF

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[1]
Macrophage migration inhibitory factor (MIF)	TT2AST1	MIF_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Carbonic anhydrase II (CA-II)	DTT	CA2	8.796	10.933	9.395	9.819

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase II (CA-II)	DTT	CA2	7.95E-08	0.52	0.33

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.