Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMPTNUQ)

Drug Name
MC-113 Drug Info
Synonyms Sigma opoid receptor agonist (oral, CNS diseases), M's Science
Indication
Disease Entry ICD 11 Status REF
Central nervous system disease 8A04-8D87 Investigative [1]
Cross-matching ID
TTD Drug ID
DMPTNUQ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Opioid receptor sigma 1 (OPRS1) TT5TPI6 SGMR1_HUMAN Agonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Opioid receptor sigma 1 (OPRS1) DTT SIGMAR1 7.092 5.716 5.411 6.434
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Central nervous system disease
ICD Disease Classification 8A04-8D87
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Opioid receptor sigma 1 (OPRS1) DTT SIGMAR1 2.77E-06 -0.12 -0.62
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82.