Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMPUKA7)

Drug Name
Caplacizumab Drug Info
Indication
Disease Entry ICD 11 Status REF
Thrombotic thrombocytopenic purpura 3B64.14 Approved [1]
Cross-matching ID
TTD Drug ID
DMPUKA7

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
von Willebrand factor (VWF) TT3SZBT VWF_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
von Willebrand factor (VWF) DTT VWF 3.459 8.185 6.67 8.541
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Thrombotic thrombocytopenic purpura
ICD Disease Classification 3B64.14
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
von Willebrand factor (VWF) DTT VWF 2.96E-01 2.47 2.08
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019