General Information of Drug (ID: DMPWB8G)

Drug Name
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Drug Info
Synonyms
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPTP; 28289-54-5; CCRIS 2186; 1,2,3,6-Tetrahydro-1-methyl-4-phenylpyridine; HSDB 6942; PYRIDINE, 1,2,3,6-TETRAHYDRO-1-METHYL-4-PHENYL-; 1-METHYL-4-PHENYL-PIPERIDINE-3-EN; UNII-9P21XSP91P; N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NSC 139654; EINECS 248-939-7; 1-Methyl-4-phenyl-1,2,3,6-tetrahydroxpyridine; BRN 0133712; CHEMBL24172; 9P21XSP91P; 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine; CHEBI:17963; 1-Methyl-4-phenyl-1,2,5,6-tetrahydropyridine; PLRACCBDVIHHLZ-UHFFFAOYSA-N
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
1388
ChEBI ID
CHEBI:17963
CAS Number
CAS 28289-54-5
TTD Drug ID
DMPWB8G

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type B (MAO-B) TTGP7BY AOFB_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Monoamine oxidase type B (MAO-B) DTT MAOB 9.367 6.907 8.237 8.409
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Monoamine oxidase type B (MAO-B) DTT MAOB 2.65E-02 1.12E-02 0.07
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Further explorations of unnatural alkaloids. J Nat Prod. 1985 Nov-Dec;48(6):878-93.