Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMRXW3U)

• Drug Name: 2-Hex-5-enyl-5-non-8-enyl-3,4-dihydro-2H-pyrrole Drug Info
• Synonyms: CHEMBL14196; 2-Hex-5-enyl-5-non-8-enyl-3,4-dihydro-2H-pyrrole; AC1LBGT2; 2-(1-Non-8-enyl)-5-(1-hex-5-enyl)-pyrroline; CTK5J4228; JRNMZRPLKGPMHB-UHFFFAOYSA-N; BDBM50284426; 2-(5-Hexenyl)-5-(8-nonenyl)-3,4-dihydro-2H-pyrrole #; 2-(1-Non-8-enyl)-5-(1-hex-5-enyl).delta.1--pyrroline

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 557705
  TTD Drug ID: DMRXW3U

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Acetylcholinesterase (AChE)	TT1RS9F	ACES_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Acetylcholinesterase (AChE)	DTT	ACHE	1.678	1.926	1.766	5.252

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Acetylcholinesterase (AChE)	DTT	ACHE	6.39E-02	-1.07	-1.15

References

• [1] Acetylcholinesterase inhibition by alkaloids of the ant's venom Monomorium minutum, Bioorg. Med. Chem. Lett. 5(11):1131-1132 (1995).