Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMS325C)

• Drug Name: 6-fluoropyridin-3-ylboronic acid Drug Info
• Synonyms: 351019-18-6; 2-Fluoropyridine-5-boronic acid; 2-Fluoro-5-pyridylboronic acid; (6-fluoropyridin-3-yl)boronic Acid; 6-fluoropyridine-3-boronic acid; 2-fluoro-5-pyridineboronic acid; 2-fluoropyridin-5-ylboronic acid; 6-fluoropyridin-3-ylboronic acid; 2-fluoropyridin-5-boronic acid; 6-Fluoro-3-pyridinylboronic acid; 6-Fluoro-3-pyridylboronic Acid; 6-fluoropyridin-3-yl-3-boronic acid; 6-FLUORO-3-PYRIDINEBORONIC ACID; (6-fluoropyridin-3-yl)boranediol; BORONIC ACID, (6-FLUORO-3-PYRIDINYL)-; (6-fluoro-3-pyridyl)boronic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 2783397
  CAS Number: CAS 351019-18-6
  TTD Drug ID: DMS325C

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Fatty acid amide hydrolase (FAAH)	DTT	FAAH	5.744	5.044	4.818	5.984

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

References

• [1] Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase. J Med Chem. 2008 Nov 27;51(22):7057-60.