Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMS7YF6)

Drug Name
1-(2-(naphthalen-2-yl)ethyl)piperazine Drug Info
Synonyms 1-(2-(naphthalen-2-yl)ethyl)piperazine; CHEMBL503234; 194943-70-9; SCHEMBL8671948; BDBM50278561; ZINC40379086; AKOS011777831; DA-08636
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44592243
TTD Drug ID
DMS7YF6

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serotonin transporter (SERT) TT3ROYC SC6A4_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Serotonin transporter (SERT) DTT SLC6A4 6.278 5.469 6.075 6.966
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Serotonin transporter (SERT) DTT SLC6A4 8.76E-01 7.18E-05 6.19E-04
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Design and optimization of selective serotonin re-uptake inhibitors with high synthetic accessibility. Part 1. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2329-32.