Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMSFXEO)

Drug Name

(2R,5R)-delta-methyl-alpha-acetylenic putrescine Drug Info

Synonyms

6-Heptyne-2,5-diamine; Methylacetylenic putrescine; Methyl-acetylenicputrescine; Mdl 72175; 8-Methyl-8-acetylenic putrescine; delta-Methyl-alpha acetylene putrescine; Hept-6-yne-2,5-diamine; MDL-72175; AC1L3U4J; 81645-70-7; SCHEMBL4808395; CTK5F9486; AC1Q2832; AKOS006338563; 1-Ethynyl-4-methyl-1,4-butanediamine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 122175
CAS Number: CAS 81645-70-7
TTD Drug ID: DMSFXEO

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ornithine decarboxylase (ODC1)	TTUMGNO	DCOR_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Ornithine decarboxylase (ODC1)	DTT	ODC1	9.956	8.598	9.482	8.752

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Ornithine decarboxylase (ODC1)	DTT	ODC1	5.20E-35	1.58	2.43

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Plasmodium falciparum and Plasmodium berghei: effects of ornithine decarboxylase inhibitors on erythrocytic schizogony. Exp Parasitol. 1987 Oct;64(2):237-43.