Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMT1OAH)

Drug Name
SCH-23390 Drug Info
Synonyms
Sch-23388; Lopac-D-054; AC1O7G1X; GTPL956; CHEMBL63321; SCH 23388 (S-enantiomer); SCHEMBL11107859; BDBM82248; GOTMKOSCLKVOGG-HNNXBMFYSA-N; ZINC2017840; PDSP1_001624; PDSP2_001608; PDSP2_000613; PDSP1_000616; NCGC00015301-01; (+)-SCH-23390; CAS_73445-63-3; (5S)-8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol; (1S)-7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol
Cross-matching ID
PubChem CID
5018
ChEBI ID
CHEBI:73297
TTD Drug ID
DMT1OAH

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine D1 receptor (D1R) TTZFYLI DRD1_HUMAN Antagonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Dopamine D1 receptor (D1R) DTT DRD1 5.04 4.626 2.459 1.322
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Dopamine D1 receptor (D1R) DTT DRD1 2.79E-02 -0.53 -0.53
Dopamine D1 receptor (D1R) DTT DRD1 4.77E-01 0.1 0.26
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Dopamine modulates effort-based decision making in rats. Behav Neurosci. 2009 Apr;123(2):242-51.