General Information of Drug (ID: DMTQP3V)

Drug Name
NSC-50187 Drug Info
Synonyms
4'-Methoxyflavanone; Flavanone, 4'-methoxy-; 3034-08-0; 2-(4-methoxyphenyl)chroman-4-one; NSC-50187; NSC50187; 97005-76-0; 2-(4-Methoxy-phenyl)-chroman-4-one; CHEMBL241909; 2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(4-methoxyphenyl)-; ST070122; 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(4-methoxyphenyl)-, (S)-; 4''-Methoxyflavanone; AC1Q6KJS; AC1L2TV7; Oprea1_176638; Oprea1_635195; MLS000574900; SCHEMBL127704; MEGxp0_001700; CTK4G4994; CHEBI:63329; ACon1_000211; QIUYUYOXCGBABP-UHFFFAOYSA-N
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
102928
ChEBI ID
CHEBI:63329
CAS Number
CAS 3034-08-0
TTD Drug ID
DMTQP3V

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type B (MAO-B) TTGP7BY AOFB_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Monoamine oxidase type B (MAO-B) DTT MAOB 9.367 6.907 8.237 8.409
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Monoamine oxidase type B (MAO-B) DTT MAOB 2.65E-02 1.12E-02 0.07
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors. Bioorg Med Chem. 2010 Feb;18(3):1273-9.