General Information of Drug (ID: DMU3A57)

Drug Name
AR-C70484XX Drug Info
Synonyms
CHEMBL30108; AR-C70484XX; SCHEMBL3688521; BDBM50110846; 4-[3-[4-(Decyloxy)phenoxy]acetonyloxy]benzoic acid; 4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-benzoic acid; 4-(3-(4-(decyloxy)phenoxy)-2-oxopropoxy)benzoic acid; 4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-benzoic acid(AR-C70484XX)
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
9846199
TTD Drug ID
DMU3A57

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cytosolic phospholipase A2 (GIVA cPLA2) TTT1JVS PA24A_HUMAN Inhibitor [1]
Fatty acid amide hydrolase (FAAH) TTDP1UC NOUNIPROTAC Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Fatty acid amide hydrolase (FAAH) DTT FAAH 5.744 5.044 4.818 5.984
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Fatty acid amide hydrolase (FAAH) DTT NO-GeName 2.65E-01 0.02 0.1
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 1-Indol-1-yl-propan-2-ones and related heterocyclic compounds as dual inhibitors of cytosolic phospholipase A(2)alpha and fatty acid amide hydrolase. Bioorg Med Chem. 2010 Jan 15;18(2):945-52.