Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMU9F7K)

Drug Name

S-2-(o-toluidino)-2-oxoethyl carbamothioate Drug Info

Synonyms

5429-04-9; carbamoylsulfanyl-acetic acid o-toluidide; NSC13347; AC1L5DGT; AC1Q5NMD; Oprea1_302154; MLS000085728; CHEMBL236685; ZINC69645; MolPort-002-702-780; HMS2293B23; STK795741; carbamothioic acid, s-[2-[(2-methylphenyl)amino]-2-oxoethyl] ester; NSC-13347; AKOS001735942; MCULE-9952660100; SMR000020857; EU-0051903; SR-01000520769; SR-01000520769-1; S-[2-(2-methylanilino)-2-oxoethyl] carbamothioate; S-{2-[(2-methylphenyl)amino]-2-oxoethyl} thiocarbamate; S-{2-[(2-methylphenyl)amino]-2-oxoethyl} carbamothioate; A1844/0077558

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 224667
CAS Number: CAS 5429-04-9
TTD Drug ID: DMU9F7K

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosinase (TYR)	TTULVH8	TYRO_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Tyrosinase (TYR)	DTT	TYR	5.959	5.711	5.973	4.912

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tyrosinase (TYR)	DTT	TYR	6.68E-04	2.54	1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Discovery of small-molecule inhibitors of tyrosinase. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6871-5.