Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMUL4PE)

Drug Name
MMB-4 Drug Info
Synonyms Acetocholinesterase reactivator (poison intoxication), SwRI; Dimethanesulfonate (poison intoxication), SwRI
Indication
Disease Entry ICD 11 Status REF
Poison intoxication NE6Z Investigative [1]
Cross-matching ID
PubChem CID
135545784
CAS Number
CAS 2058-89-1
TTD Drug ID
DMUL4PE

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Acetylcholinesterase (AChE) TT1RS9F ACES_HUMAN Activator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Acetylcholinesterase (AChE) DTT ACHE 1.678 1.926 1.766 5.252
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Poison intoxication
ICD Disease Classification NE6Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Acetylcholinesterase (AChE) DTT ACHE 6.39E-02 -1.07 -1.15
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2465).