Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMUZL3J)

Drug Name

N-(2,3-DIFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE Drug Info

Synonyms

N-(2,3-DIFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE; N-[(2,3-difluorophenyl)methyl]-4-sulfamoylbenzamide; F2B; N-(2,3-Difluorobenzyl)-4-sulfamoylbenzamide; 235088-49-0; 2,3-difluoro-SBB; AC1L1C1I; CTK0I7898; BDBM12016; DTXSID80274323; 1g52; 1g46; AKOS030577745; DB07742; Benzamide, 4-(aminosulfonyl)-N-[(2,3-difluorophenyl)methyl]-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 1700
CAS Number: CAS 235088-49-0
TTD Drug ID: DMUZL3J

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Carbonic anhydrase II (CA-II)	TTANPDJ	CAH2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Carbonic anhydrase II (CA-II)	DTT	CA2	8.796	10.933	9.395	9.819

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Carbonic anhydrase II (CA-II)	DTT	CA2	7.95E-08	0.52	0.33

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.