Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMW0Y75)

Drug Name
ISIS 150454 Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DMW0Y75

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SOD1 messenger RNA (SOD1 mRNA) TTP9K3Q SODC_HUMAN Not Available [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
SOD1 messenger RNA (SOD1 mRNA) DTT SOD1 11.785 10.388 11.246 11.267
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
SOD1 messenger RNA (SOD1 mRNA) DTT SOD1 2.51E-01 -0.49 -0.43
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 US patent application no. 7,132,530, Antisense modulation of superoxide dismutase 1, soluble expression.