Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMW6U7K)

Drug Name

CHOLINE IODIDE Drug Info

Synonyms

Choline iodide; 17773-10-3; 2-Hydroxy-N,N,N-trimethylethanaminium iodide; Jodoetano; Dilatol zambon; UNII-39528O55VK; EINECS 241-754-2; (2-Hydroxyethyl)trimethylammonium Iodide; AI3-61505; CHEMBL293410; Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, iodide; 39528O55VK; CholineIodide; AC1L3DCR; AC1Q1TNR; ACMC-209ed9; SCHEMBL315876; CTK4D6569; ANW-22891; MFCD00011900; AKOS027320917; 2-hydroxyethyl(trimethyl)azanium iodide; ACM17773103; KS-0000140P; LS-53247; KB-76072; TC-111636; FT-0623771; C-45721; Ethanaminium,2-hydroxy-N,N,N-trimethyl-, io

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 87300
CAS Number: CAS 17773-10-3
TTD Drug ID: DMW6U7K

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Acetylcholinesterase (AChE)	TT1RS9F	ACES_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Acetylcholinesterase (AChE)	DTT	ACHE	1.678	1.926	1.766	5.252

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Acetylcholinesterase (AChE)	DTT	ACHE	6.39E-02	-1.07	-1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Structure-based alignment and comparative molecular field analysis of acetylcholinesterase inhibitors. J Med Chem. 1996 Dec 20;39(26):5064-71.