Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMW8KI7)

Drug Name

Insulin Susp Isophane Recombinant Human Drug Info

Synonyms

Nph Insulin; Nph Iletin I (Beef-pork); Nph Iletin Ii; Insulin Insulatard Nph Nordisk; Nph Iletin Ii (Pork); Nph Purified Pork Isophane Insulin; Humulin N; Novolin N; Insulatard Nph Human; Insulin Susp Isophane Beef; Insulin Susp Isophane Beef/Pork; Insulin Susp Isophane Purified Beef; Insulin Susp Isophane Purified Pork; Insulin Susp Isophane Semisynthetic Purified Human

Indication

Disease Entry	ICD 11	Status	REF
Diabetic complication	5A2Y	Approved	[1]

Cross-matching ID

TTD Drug ID: DMW8KI7

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Insulin (INS)	TTZOPHG	INS_HUMAN	Modulator	[2]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Insulin (INS)	DTT	INS	0.848	2.138	0.379	0.926

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Diabetic complication

ICD Disease Classification

5A2Y

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Insulin (INS)	DTT	INS	6.70E-01	-0.12	-0.46

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.