Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMWCQP4)

• Drug Name: Interferon Alfa-2b Drug Info
• Synonyms: Intron A; Viraferon

Indication

Disease Entry	ICD 11	Status	REF
Melanoma	2C30	Approved	[1]

• Therapeutic Class: Anticancer Agents
• Cross-matching ID:
  PubChem CID: 71306834
  CAS Number: CAS 98530-12-2
  TTD Drug ID: DMWCQP4
  ACDINA Drug ID: D01166

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interferon-alpha 2 (IFNA2)	TTSIUJ9	IFNA2_HUMAN	Modulator	[2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Interferon-alpha 2 (IFNA2)	DTT	IFNA2	2.609	1.678	0.263	0.379

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Melanoma
• ICD Disease Classification: 2C30

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Interferon-alpha 2 (IFNA2)	DTT	IFNA2	9.31E-04	0.35	2.05

References

• [1] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
• [2] Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.