Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMWEKBD)

• Drug Name: Phenyl-1,4-bismaleimide Drug Info
• Synonyms: 3278-31-7; N,N'-1,4-Phenylenedimaleimide; N,N'-p-Phenylenedimaleimide; N,N'-4-Phenylenedimaleimide; phenyl-1,4-bismaleimide; UNII-BEC7P1E6J1; 1,1'-(1,4-phenylene)bis(1h-pyrrole-2,5-dione); BEC7P1E6J1; n,n-1,4-phenylenedimaleimide; CHEMBL576594; 1,1'-Benzene-1,4-diylbis(1H-pyrrole-2,5-dione); 1-[4-(2,5-dioxopyrrol-1-yl)phenyl]pyrrole-2,5-dione; NSC81257; EINECS 221-910-6; NSC 81257; p-PDM; 1,4-Dimaleimidobenzene; ACMC-209hvr; AC1Q6MZN; 1,4-phenylene dimaleimide; 1,4-bis(maleimido)benzene; AC1L2RM9; SCHEMBL95324

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 76765
  CAS Number: CAS 3278-31-7
  TTD Drug ID: DMWEKBD

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Fatty acid amide hydrolase (FAAH)	TTDP1UC	NOUNIPROTAC	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Fatty acid amide hydrolase (FAAH)	DTT	FAAH	5.744	5.044	4.818	5.984

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Fatty acid amide hydrolase (FAAH)	DTT	NO-GeName	2.65E-01	0.02	0.1

References

• [1] Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors. J Med Chem. 2009 Dec 10;52(23):7410-20.