Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMWFHKR)

Drug Name
4-oxadiazole derivative 1 Drug Info
Synonyms PMID25470667-Compound-Figure5-11
Cross-matching ID
TTD Drug ID
DMWFHKR

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 7 receptor (HTR7) TTO9X1H 5HT7R_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
5-HT 7 receptor (HTR7) DTT HTR7 1.561 1.233 0.848 1.485
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
5-HT 7 receptor (HTR7) DTT HTR7 4.97E-02 -0.03 -0.11
5-HT 7 receptor (HTR7) DTT HTR7 3.78E-01 -4.84E-04 -3.66E-03
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Acyltransferase inhibitors: a patent review (2010-present).Expert Opin Ther Pat. 2015 Feb;25(2):145-58.