General Information of Drug (ID: DMWI7XJ)

Drug Name
5-Phenethyl-quinazoline-2,4-diamine Drug Info
Synonyms
CHEMBL341703; 5-phenethylquinazoline-2,4-diamine; 5-Phenethyl-quinazoline-2,4-diamine; AC1LALFL; CTK7E0789; BDBM50036483; ZINC13740535; 5-(2-phenylethyl)quinazoline-2,4-diamine; 5-(2-phenylethyl)-2,4-quinazolinediamine; 2,4-Diamino-5-(2-phenylethyl)-quinazoline; (2-amino-5-phenethyl-quinazolin-4-yl)-amine; 2,4-Quinazolinediamine, 5-(2-phenylethyl)-
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
490662
TTD Drug ID
DMWI7XJ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Polypeptide deformylase (PDF) TT9SL3Q DEFM_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Polypeptide deformylase (PDF) DTT PDF 8.87E-16 -0.54 -0.86
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 2,4-Diamino-5-substituted-quinazolines as inhibitors of a human dihydrofolate reductase with a site-directed mutation at position 22 and of the dih... J Med Chem. 1995 Mar 3;38(5):745-52.