Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMWS35F)

Drug Name

(4-((1H-imidazol-1-yl)methyl)phenyl)methanol Drug Info

Synonyms

[4-(1H-Imidazol-1-ylmethyl)phenyl]methanol; 103573-92-8; CHEMBL590987; (4-((1H-imidazol-1-yl)methyl)phenyl)methanol; {4-[(1H-Imidazol-1-yl)methyl]phenyl}methanol; [4-(imidazol-1-ylmethyl)phenyl]methanol; SCHEMBL10661787; CTK8G4735; DTXSID80575387; FSLVBXCLXDGFRE-UHFFFAOYSA-N; MolPort-000-143-260; SBB090788; ZINC12370277; BDBM50307211; AKOS006344218; RP03593; [4-(imidazolylmethyl)phenyl]methan-1-ol; KB-63739; DB-059022; 4-(1H-Imidazole-1-ylmethyl)benzenemethanol; Y6875; FT-0708208; 4-((1H-imidazol-1-yl)methyl)phenylmethanol

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 15594569
CAS Number: CAS 103573-92-8
TTD Drug ID: DMWS35F

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Steroid 11-beta-hydroxylase (CYP11B1)	TTIQUX7	C11B1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Steroid 11-beta-hydroxylase (CYP11B1)	DTT	CYP11B1	5.647	4.954	5.678	6.194

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Steroid 11-beta-hydroxylase (CYP11B1)	DTT	CYP11B1	4.31E-04	-0.03	-0.13

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25.