General Information of Drug (ID: DMWVS5X)

Drug Name
JWH-250 Drug Info
Synonyms
864445-43-2; 2-(2-Methoxyphenyl)-1-(1-pentyl-1H-indol-3-yl)ethanone; JWH-250; 2-(2-methoxyphenyl)-1-(1-pentylindol-3-yl)ethanone; UNII-IP9911R8A0; CHEMBL188031; FFLSJIQJQKDDCM-UHFFFAOYSA-N; IP9911R8A0; Q-200139; 1-Pentyl-3-(2-methoxyphenylacetyl)indole; DEA No. 6250; SCHEMBL11983322; CTK8C5059; JWH 250; DTXSID40235556; MolPort-009-019-586; KS-000024QU; ANW-73903; ZINC28465020; MFCD12911796; BDBM50170335; AKOS015999864; DS-3158; CCG-208724; NCGC00386575-01; AJ-83461; CJ-17680; AK-82232; AN-26990; KB-110367; TC-162648; ST24021676
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44397540
CAS Number
CAS 864445-43-2
TTD Drug ID
DMWVS5X

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cannabinoid receptor 2 (CB2) TTMSFAW CNR2_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Cannabinoid receptor 2 (CB2) DTT CNR2 7.037 6.733 6.944 7.163
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Cannabinoid receptor 2 (CB2) DTT CNR2 3.82E-02 -0.43 -1.18
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4110-3.