Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMX32JY)

Drug Name
ED45 Drug Info
Indication
Disease Entry ICD 11 Status REF
Acute respiratory distress syndrome CB00 Investigative [1]
Myocardial reperfusion injury NB31 Investigative [1]
Sepsis 1G40-1G41 Investigative [1]
Cross-matching ID
TTD Drug ID
DMX32JY

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neutrophil elastase (NE) TTPLTSQ ELNE_HUMAN Not Available [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Neutrophil elastase (NE) DTT ELANE 2.379 2.036 1.379 2.945
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Acute respiratory distress syndrome
ICD Disease Classification CB00
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Neutrophil elastase (NE) DTT ELANE 2.35E-01 -0.55 -0.82
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Therapeutic applications of aptamers. Expert Opin Investig Drugs. 2008 Jan;17(1):43-60.