Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXO98C)

Drug Name

3-hydroxy-N,N,N-trimethylbenzenaminium iodide Drug Info

Synonyms

TMPH; 3-(Trimethylammonio)phenol iodide; m-(Dimethylamino)phenol methiodide; 3-Hydroxy-N,N,N-trimethylbenzenaminium iodide; 3-Oxyphenyl trimethylammonium iodide; (m-Hydroxyphenyl)trimethylammonium iodide; CHEMBL37773; AMMONIUM, (m-HYDROXYPHENYL)TRIMETHYL-, IODIDE; 2498-27-3; 3483-84-9 (Parent); 3-Hydroxyphenyltrimethylammonium Iodide; AC1L29MQ; Benzenaminium, 3-hydroxy-N,N,N-trimethyl-, iodide; KNPHMCQIKGHPRU-UHFFFAOYSA-N; m-hydroxyphenyltrimethylammonium iodide; LS-18453; (3-hydroxyphenyl)-trimethylazanium iodide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 17250
CAS Number: CAS 2498-27-3
TTD Drug ID: DMXO98C

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Acetylcholinesterase (AChE)	TT1RS9F	ACES_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Acetylcholinesterase (AChE)	DTT	ACHE	1.678	1.926	1.766	5.252

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Acetylcholinesterase (AChE)	DTT	ACHE	6.39E-02	-1.07	-1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors. Bioorg Med Chem. 2008 Aug 1;16(15):7450-6.