Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXQROU)

Drug Name

3-(2,4-dihydroxyphenyl)propionic acid Drug Info

Synonyms

5631-68-5; 3-(2,4-dihydroxyphenyl)propanoic acid; 3-(2,4-Dihydroxyphenyl)propionic acid; Hydroumbellic acid; Benzenepropanoic acid, 2,4-dihydroxy-; CHEMBL228155; 2,4-Dihydroxybenzenepropanoic acid; AI3-13072; AC1L3WC8; AC1Q5VW7; NCIOpen2_000618; SCHEMBL490491; ACMC-1B046; 2,4-Dihydroxyhydrocinnamic acid; CTK5A4966; DTXSID50204854; MolPort-000-877-529; HMCMTJPPXSGYJY-UHFFFAOYSA-N; ZINC388556; NSC71551; KS-00000N9R; NSC-71551; BDBM50211056; STL034241; SBB068271; BBL028276; Benzenepropanoic acid,2,4-dihydroxy-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 96384
CAS Number: CAS 5631-68-5
TTD Drug ID: DMXQROU

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosinase (TYR)	TTULVH8	TYRO_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Tyrosinase (TYR)	DTT	TYR	5.959	5.711	5.973	4.912

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Tyrosinase (TYR)	DTT	TYR	6.68E-04	2.54	1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Enhanced substituted resorcinol hydrophobicity augments tyrosinase inhibition potency. J Med Chem. 2007 May 31;50(11):2676-81.